deranger

It only makes prodrugs that first need to be metabolized by CYP3A4 to be active less effective. This is a pretty small minority of drugs. It makes drugs that are inactivated by CYP3A4 more effective, which is the majority of them. It also only competitively inhibits the enzyme while the drug is in your system, it’s not permanently inhibiting the enzyme like a suicide inhibitor.

Would you look at the P on that beam!

Absolutely. I never really thought much of OCZ to begin with, and sure it was a very early SSD, but damn. It crapped out way early the first time, at least in terms of I/O, and the second time it died it was just outside of RMA eligibility. Never again.

One of those.

And you had to get the partition aligned (?) when you formatted it. I had a 120GB OCZ Agility I paid like $380 for. It was amazing loading in way before everyone in games, I remember always being first in my WoW clan raids. Left 4 Dead 2 also ripped on that SSD. It died within a year and the RMA replacement died within year as well. RIP

Still Wakes the Deep. Shit goes wrong on a Scottish oil rig in the 70s, it’s sorta like dead space mixed with alien isolation and a walking simulator. Stealth gameplay with some puzzles and a decent emotional narrative. I had a good time playing it and it’s on gamepass. Short and sweet.

I really doubt they’re listening to your microphone. Constantly uploading your audio would be noticeable in bandwidth and constantly analyzing audio on device would kill your battery - at least currently.

What this demonstrates is how good tracking by other methods is getting. You don’t need to listen to someone’s microphone when you know what they and their friends/coworkers are looking up online and likely bringing up in conversation. It’s trivial to fingerprint someone and track near everything they’re looking up online, and even if you’re privacy conscious, many of those you associate with share their contact list with every app that asks for it. This makes suggesting things your friends are looking up pretty easy. Add a bit of confirmation bias to the mix and you’ve got this “listening to the microphone” theory, because you’re not counting the number of times an ad isn’t something you’ve been recently discussing.

You could say the same thing for any Fallout/Elder Scrolls game, too. 'Boring ride through the country' < oblivion and Skyrim. 'Boring walk to the next area' <Fallout

Exploration is one of the most enjoyable parts of those games. It’s not boring in ES or FO because of all the things you find along the way. Walking from A to B and getting distracted for 2 hours at random POIs you find is a hallmark of these games.

This aspect was completely absent in Starfield, idk how they fucked up exploration so much.

it's a literal SPACE exploration game, how can you complain about travelling through space

Traveling != exploration. Eliminating the load screens just leaves you in boring space with no POIs to discover along the route.

It still works pretty well, not as effective as regular external NC of course, but the difference between transparency and isolation modes when chewing crunchy foods or using my electric toothbrush is very noticeable. Now I’m going to have to do a bit of an experiment with bone conduction headphones from a friend and ANC mode to see how well it’s working.

Some headphones now have internal noise cancellation, such as AirPods Pro and Max. I can hear it working when I’m chewing something crunchy or when I’m using my electric toothbrush and toggling between transparency and NC modes. Kinda curious if some other cans have this as well, it’s a nice feature. There are microphones inside the cup listening to internal sounds and cancelling those out as well as external sounds.

You can start a forest fire if said forest is used for cover or concealment by enemy military forces. All feasible precautions must be taken to limit the damage to military targets only.