It really does!
Just the shift in cerebrospinal fluid in response to progesterone explains not just the obvious symptoms that come with that part of the cycle, it points to things like increased migraines, memory issues, and that's huge.
Having a correlation shown like this could possibly revolutionize how women get care. Just the correlation. If there's a definitive causation, just the ability to better customize hormone regimens in birth control could improve millions of lives.
Considering the extremes I've seen women in my life go through with no real ability to get predictable results from medical assistance relating to their cycles, this is fantastic news.
I mean, it can.
Someone not used to it, taking a high dose can end up with nausea, vomiting, etc.
Even long term potheads can have bad results with too high a dose. Then there's rare reactions, allergies, etc.