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I expect gene editing soon to become so cheap that everyone starts customising their children, resulting in a situation analogous to where dogs are now: extreme variability improving the chances for survival by making sure we have the needed people for any situation except gamma ray burst which requires backups far from Earth.
I've been working on a sci Fi show where humans have this but they also have the ability to change their current physiology by infecting themselves with modified strains of cancer that slowly replaces you're body with one you downloaded off the Internet this technology has also sorta obsoleted medicine because if you have a broken leg or infected with a fatel desese so long as the injury doesn't affect your brain you can just replace your entire body by infecting yourself with genetically modified cancer