this post was submitted on 09 Jan 2024
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covid

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Looks like there's gonna be a lot more pneumonia this round.

Highly mutated COVID variant BA.2.86—close ancestor of globally dominant “Pirola” JN.1—may lead to more severe disease than other Omicron variants, according to two new studies published Monday in the journal Cell.

In one study, researchers from Ohio State University performed a variety of experiments using a BA.2.86 pseudovirus—a lab-created version that isn’t infectious. They found that BA.2.86 can fuse to human cells more efficiently and infect cells that line the lower lung—traits that may make it more similar to initial, pre-Omicron strains that were more deadly.

In the other study, researchers in Germany and France came to the same conclusion. “BA.2.86 has regained a trait characteristic of early SARS-CoV-2 lineages: robust lung cell entry,” the authors wrote. The variant “might constitute an elevated health threat as compared to previous Omicron sublineages,” they added.

We're up to 2000 a week dying from covid in the US, and that's probably an undercount due to lots of people, hospitals and states pretending covid is just a cold or doesn't exist anymore.

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[–] [email protected] 3 points 10 months ago* (last edited 10 months ago)