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A Popular Sweetener Was Linked to Increased Anxiety in Generations of Mice (www.sciencealert.com)

submitted 11 months ago by [email protected] to c/[email protected]

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[–] [email protected] 4 points 11 months ago* (last edited 11 months ago) (1 children)

Digestive issues aside I'm mostly concerned with the evidenced increased risk of stroke and heart-attack.

https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-is-erythritol-a-safe-and-healthy-sugar-substitute/

In recent decades, some concerning research has been published about possible adverse health effects of erythritol.

An American study from 2001 found that people who used erythritol as a sweetener had a three-year increased risk of major adverse cardiac events – defined as non-fatal heart attack or stroke. While this was an incidental finding – meaning that the erythritol did not necessarily cause or contribute to their cardiac issues – it highlighted the need for more research to determine if using a sugar substitute predisposes a person to higher heart attack or stroke rates.

A 2021 study examined people who consumed erythritol or a similar sugar alcohol, xylitol. The results found that ingesting erythritol as a sugar substitute caused a spike in blood levels and increased the stickiness of the volunteers’ platelets. Platelets help the blood to clot if we cut ourselves, but if they are sticky, the risk of blood clots in the body increases, raising our risk of heart attack, stroke or other vascular issues.

While the findings still do not definitely prove that erythritol directly increases the risk for cardiovascular issues, the results indicate it may be best to avoid it until we have more evidence to suggest that it is or is not safe.

[–] [email protected] 6 points 11 months ago (1 children)

I can't find it anywhere on there but does it control for Obesity?

Most people who want a sugar alternative already have high rates of cardiac events.

[–] [email protected] 1 points 11 months ago (1 children)

A fair point that I don't know but further begs the question why that's not found in other sugar alternative studies.

[–] [email protected] 2 points 11 months ago* (last edited 11 months ago)

Do we know that? I don't see that anywhere in the article or the source

I don't even see it has increased risk compared to regular sugar. Just "increased".