I was going for a Portal 1 GLaDOS there. Portal 2 GLaDOS be like:

Today we are focusing on material integrity--YOURS to be more precise. In this chamber you will encounter a long track of propulsion gel, at the end of which you will encounter an Aperture Science Particle Filtration Grid. The goal isn't to stop you; it is to see precisely which parts of you stop. For science.

Now, try not to disappoint. Or do; it really doesn't matter to me. And if you somehow manage to reassemble yourself on the other side, do let us know. It would be...unexpected

Cave Johnson be like:

Alright, listen up down there! This next experiment we call The Sift. Now you might be thinking, "Cave, why am I being forced through a giant cheese grater?" The answer is very simple: Because you signed the waiver.

We're throwing science at the wall to see what sticks. And by 'the wall' we mean the Aperture Science Particle Filtration Grid, and by 'science' we mean you. And by 'throw' we mean 'fire out of a giant pneumatic cannon."

Some of you might be worried about the finer points, the technical details. Don't! That's our job. Your job is to be the organic matter. I'll be honest, some of you will make it through, and some of you won't. You won't have any tumors left after this, so you've got that going for you. Caroline, start the compressor.