this post was submitted on 18 Aug 2024
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Probably not a problem for everyone but it was a problem I was running into where my meds weren't being as effective towards the bottom of the bottle and then would work great after a refill.

My meds are supposed to be stored between 67F and 77F and my apartment has been routinely getting to around 85F for days (and weeks) at a time and by the time I was getting close to the bottom of the bottle it wasn't really working that well for me.

So I took one of those can fridges and added some temperature control to it to automatically keep it in the temperature range I need and also added a large bag of dessicant in there to keep the humidity low as those little can fridges suck up moisture something fierce.

So basically make sure your meds are stored properly or you'll probably have some additional issues that you really don't need.

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[–] [email protected] 6 points 2 months ago (1 children)

10F is quite large from a chemical stability point of view.

[–] [email protected] -1 points 2 months ago (2 children)

No, especially not for amphetamine salts.

[–] [email protected] 1 points 2 months ago (1 children)

Because of your opinion based on what?

[–] [email protected] 3 points 2 months ago (2 children)

More probable than OP's opinion based purely from "how hard that shit hits bro".

Like, theres so many different reasons for OP's feelings rather than a couple degrees temperature difference. Even a slight difference in stomach pH would have a bigger impact on the bioavailability than any non-excessive variations in storage temperature would.

And let's say that even if that small amount of temperature has any real impact, it wouldn't be noticeable either unless OP's prescription is like a year's worth of product for each refill. But sure, love the echo chamber down votes, nothing wrong with believing OP's blind opinions... you're surely gonna notice a helluva difference when you're temperature controlling one of the most chemically stable medicines!

[–] [email protected] 2 points 2 months ago* (last edited 2 months ago) (1 children)

Also - I mean that's not really what that study says... They kept it at 71°f. Which is still within the controlled temperature. It's not 85°f.

So good job googling after the fact to prove what you didn't actually know and still being wrong

[–] [email protected] 0 points 2 months ago (1 children)

Yeah, just ignore that they stored it at 40 freedom temperatures, which is a lot outside the suggested storage range, and had no impact. So OP's +15F difference would most likely not be some game changer of a very stable chemical; many other factors have a much bigger effect on bioavailability, and that's what you should be focusing on instead.

[–] [email protected] 0 points 2 months ago* (last edited 2 months ago)

Okay but no one is saying refrigeration is denaturing it in this thread and no I won't just focus on what you want because you say so

[–] [email protected] 1 points 2 months ago* (last edited 2 months ago) (1 children)

Yeah echo chamber uh huh.

Or hear me out. People don't like people who just say "nuh uh sorry you're 'not getting your fix bro'" without anything to back it up.

[–] [email protected] 0 points 2 months ago

I didn't make any accusations, I simply asked what they were basing his opinion on.

[–] [email protected] -1 points 2 months ago

Keeping it at a stable temperature could improve its placebo effect 😅