Takes like this are one of the many things I pull out to point out how naive and misguided most x-risk obsessive people are. And especially Mr. Altman.
Despite wide fears of synthetic gain of function attacks, as it turns out, it's actually really hard to create a new virus meaningfully stronger than the standard endemic ones that already exist. Many countries and labs have legitimately tried. Lots of papers and research. It's, really really hard to beat nature at the microbiological scale; Viruses have to not only be virulent, but it has to contend with extremely unpredictable intermediate environments. The current endemic viruses got there through many mutations and adaptations inside environments that they were already at least successful (and not in vitro). And in the end, what would be the point? Once a virulent virus breaks out, you have very little control. Either it works really well and backfires or, even far more likely, it doesn't do that much at all, but it does piss other nations off.
It's not impossible. But honestly, yeah, I don't comprehend x-riskers who obsess over this.
duh, duh duh, duh, duuuuuuuuuh, yup.