The newer games, particularly Elden Ring, got wayyyy better about not having to run back to the boss room.
I replayed Dark Souls 1 last year and it made me want to bash my head into the wall every time I had to hoof it back to a boss, especially in the late game.
Ayyy that's capitalism, baby!!
I beat the first act of Inscryption by making a deck that makes infinite ants. I don't remember exactly how it worked but I could sacrifice a squirrel and just spawn infinite ants. I think you're supposed to eventually break this but it was still fun as hell.
I broke the Binding of Isaac during the only successful playthrough of it that I've ever done. I had the giants foot, which randomly comes down and smashes enemies. I then had an item that made me in invincible when I stood still. So I could just walk into a room, stand in place, and wait for all the enemies to just be killed.
I know I've broken Slay the Spire multiple times, especially using the Construct. I think I also found a way to give myself infinite knives with the Silent. Again, I cant remember what specific cards I used but I played that game A LOT.
He's the best boy too. He just has to learn not to pee in the house lol.
The Metal Gear Solid series, particularly Snake Eater.
It's just so dramatic and over the top like the rest of the game.
They even wisely use it as a pallet cleanser after fighting The End and you have to climb that long ass ladder.