this post was submitted on 08 May 2025
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A combination shot would make it easier for people to get vaccinated against Covid and the flu at the same time.

Moderna’s combined Covid and flu shot outperformed the existing standalone vaccines for both viruses, according to the results of a phase 3 clinical trial published Wednesday in theJournal of the American Medical Association

The vaccine uses the same messenger RNA technology as Moderna’s approved Covid vaccine.(There are no approved mRNA-based flu shots.)

The trial, funded by Moderna, included more than 8,000 adults ages 50 and older who were enrolled in October and November 2023. For people ages 50 to 64, the new vaccine was compared to Moderna’s Covid vaccine and the flu shot Fluarix. For people 65 and older, it was compared to the Covid vaccine and a different flu shot, called Fluzone, which is a stronger dose typically given to older adults. The trial participants either got the existing shots, or the new combination vaccine plus a placebo shot. (This way, both groups got two injections.)

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[–] [email protected] 54 points 3 days ago (2 children)

I can’t wait. I love Vaccines. Science is truly amazing.

[–] [email protected] 9 points 3 days ago

The closest things to miracles we can actually do! Preserving probably millions of lives every year. It used to be normal to have a bunch of kids and just have many of them die or get crippled early in live due to child illness.

Fun fact: in Vietnam, after they kicked out the French, they changed all the French street names with some exceptions. Pasteur was one of those exceptions.

[–] [email protected] 11 points 3 days ago (2 children)

I know right? We need more comments like this to counter all the anti-vax bullshit.

I'm not just neutral on vaccines, I think they're fucking amazing and I want more.

[–] [email protected] 3 points 3 days ago (3 children)

I don't think we're going to find antivaxxers on Lemmy.

[–] nieceandtows 2 points 2 days ago (1 children)

I'm not antivax but I'm suspicious of these 'subscription' vaccines which don't eradicate the disease but only succeed in helping them mutate every year so that they can keep lining their pockets. Don't we have the scientific advancements to eradicate flu instead of playing a profitable cat and mouse every year? I'm from India, and was very surprised to hear about the annual flu shots when I first came to the US. May be I'm just cynical, and there is just no way to truly eradicate flu accounting for its mutations.

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[–] [email protected] 1 points 2 days ago

Ugh, there seems to be one in this very thread. So sick of them (no pun intended).

[–] [email protected] 1 points 3 days ago* (last edited 3 days ago)

they are all still shilling on reddit, youtube, ,,,etc.

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[–] [email protected] 76 points 4 days ago (5 children)

“Immunologically, what’s happening in each cell is they’re acting as if they’ve been infected with both viruses, and so your immune system is going to respond and make the type of inflammation that you would if you had flu or Covid or both simultaneously,” he said.

This will 100% be taken out of context by anti-vaxx crowds.

[–] [email protected] 6 points 3 days ago

It's nothing new, though. Vaccines have always worked like this - make your body go through the motions without problematic invasive organisms.

[–] [email protected] 12 points 4 days ago (2 children)

Terrible explanation as well.

[–] [email protected] 3 points 3 days ago

they should call it bivalent vaccine, since its 2 in 1.

[–] [email protected] 3 points 4 days ago (1 children)

Is it? I understood it. How would you explain it?

[–] [email protected] 16 points 4 days ago (1 children)

They use inflammation instead of antibodies for one.

[–] [email protected] 3 points 3 days ago (1 children)

Antibodies create an inflammatory response, seems like we're really nitpicking here. It's a layman's explanation, not a research study or textbook.

[–] [email protected] 3 points 3 days ago

"It does a thing to mimic the bad thing and then the thing gets better so you don't get the real thing."

[–] [email protected] 4 points 3 days ago (2 children)

honestly so fucking what? let those jokers not get the vaccination. get sick, have permanent symptoms that last your whole life, fuck it, whatever.

in the meantime, my sleeves are pre-rolled up for this shot, put it in my veins doc, I like not basically dying, its kind of a fetish

[–] [email protected] 12 points 3 days ago (3 children)

I feel like we've had this discussion a billion times since 2019... Do you really still not understand herd immunity?

[–] [email protected] 8 points 3 days ago

Since 2019 I have given up entirely on collective common sense coming from anybody. People are just far too stupid and selfish to get their shit together if it even inconveniences them a tiny bit. I can only do my best to protect myself as relying on people writ large is a fools errand.

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[–] [email protected] 3 points 3 days ago (1 children)

Good luck getting it at all. One of those jokers is head of the HHS and is actively adding obstacles to vaccine approvals.

[–] [email protected] 2 points 3 days ago

I live in Ireland ¯_(ツ)_/¯

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[–] [email protected] 18 points 3 days ago (1 children)

... unless you are in a country with a crazy antivaxxer at the helm of public health.

[–] [email protected] 1 points 2 days ago (1 children)

Well, fortunately they don't get to dictate the health policies of advanced nations.

[–] [email protected] 1 points 2 days ago

That's what I'm most glad about.

[–] [email protected] 33 points 4 days ago* (last edited 4 days ago) (2 children)

Totally gonna get it anyway but I'm not looking forward to my body throwing a 24h shitfit over it - I usually get what they call a VIGOROUS immune response from either one alone (not every year though, this last year's flu shot was actually 100% fine for some reason). One time I was an hour late on my Motrin-Tylenol rotation and the symptoms peaked 15 minutes or so after I got that delayed dose down and I just remember laying on my husband's lap and being so tired and fatigued and my bones were aching everywhere and I couldn't stop shivering and I must have just passed out because I remember suddenly waking up and feeling completely fine again. It's completely benign and controllable with over the counter medication (and undoubtedly better than catching the actual flu / COVID) but it suuucks.

[–] [email protected] 9 points 4 days ago (1 children)

As I understand it, a good immune response is a positive thing with immunizations.

[–] [email protected] 10 points 4 days ago (1 children)

Is it? All I've ever heard is that whether you're experiencing symptoms is completely irrelevant, which makes sense since the symptoms are triggered by the innate (non-specific) response and immunity is the adaptive (specific) response. Those are from what I've heard more or less completely independent.

[–] [email protected] 10 points 4 days ago* (last edited 4 days ago) (1 children)

Studies show individuals with a more robust immune response trend higher on antibody count, but you are correct to say that it doesn't necessarily correlate to no immune response = no antibodies.

https://www.bu.edu/neidl/2023/12/its-good-to-feel-bad-after-your-covid-shot/

[–] [email protected] 4 points 3 days ago* (last edited 3 days ago) (1 children)

I'm pretty sure it's because my whole body has anxiety not just my brain. My body sees a few antigens and just:

[–] [email protected] 1 points 2 days ago

Producing anxi-bodies!

[–] [email protected] 3 points 3 days ago

I'm in a similar place. The MRNA vaccines trigger a very strong immune response and I don't know if I want to go through it again. It sucks, and the non-mrna options offer at least comparable to slightly reduced protection. Which given my age is generally adequate

[–] [email protected] 10 points 3 days ago (1 children)

Does this mean we're still getting a flu shot this year in the US? Last I heard RFK cancelled everything for them

[–] [email protected] 1 points 3 days ago

the current flu season is almost ending, i heard the next vaccine/season is around september

[–] [email protected] 8 points 3 days ago

Not if the brain worms have anything to say about it

[–] [email protected] 1 points 2 days ago (1 children)

So... Whats this about covid shot causing heart problems? Propaganda or true?

I imagine having full COVID causes more heart and lung problems than the shot ever would.

[–] [email protected] 5 points 2 days ago

Yes.

It has reportedly caused myocarditis in some people, and they generally recover.

However:

for every 100 000 vaccinated, compared to about four more cases of myocarditis we have 56 fewer hospitalizations, 13.8 admissions to intensive care and 0.6 fewer deaths.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9653149/

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