A few thoughts:
- Unlike reddit, Lemmy provides a way for instances to not tolerate those sorts of activities by limiting what users can join their own instances and blocking entire instances where those activities are coming from.
- With karma not being a public profile stat, there shouldn't be any needs to farm it.
- Without the corporate profit motive and centralized control Lemmy (as a whole) couldn't do what reddit is doing with the APIs. An instance could and an instance could also serve ads, but people are free to move to another instance if they don't like it while still maintaining access to most content.