I finally finished the dresser I've been working on (it's #2 of 2, built to fit in our closet). No drawer slides, just paste wax, and made pretty much entirely from plywood and glue.
The project was pretty simple, but I went for (fairly) tight tolerances (a few mm clearance), so I was grateful for having made a crosscut sled on this one.
It slides really nicely without them, and doing it this way made each drawer about 5cm wider, which is a nice space bump. The other one opens quite well when fully loaded with heavy clothes. I hand-planed and waxed the drawer slides, so it's quite smooth. I was a little worried, too, but figured I'd give it a shot.