Running it on a 7Pro now, a 6Pro prior as well as a 5a and 4a before those. I wouldn't run a Pixel any other way.
Since we've got the sandboxed play services I've yet to find a single downside running Graphene, which you can't say about almost any other custom OS. Everything works, purchased apps work, and you get all the benefits of Graphene without all the downsides of Google. If I couldn't have a Pixel running Graphene, I'd probably deal with an iPhone. No way I'd run a stock Google ROM.