So did the events of “All Good Things…” actually occur or did the temporal incursion being fixed rendered it non-existent? After all, Q was testing Jean-Luc. Only Jean-Luc had memory of what happened. Sub-question: did Jean-Luc actually have a correctly diagnosed irumodic syndrome in the anti-timeline future?
Yes. Although it is implied that the extent of the Q testing Picard was by pushing him to cause the problem in the first place, rather than creating it themselves, so that he would realise how it could be fixed, as an example of human thinking beyond their expectations.
We see in Trek that the future is always in Flux. While he had Irumodic syndrome in that future or something like it, in the present, it wasn't actually, but something else like it. There may be a thousand things that could have caused it, that we're not privy to. A space anomaly happens about once a week, and the manifestation of Irumodic syndrome itself might only have happened by chance, like the anti-time anomaly preventing the formation of life on Earth.
At the very least, in the future, there seemed to be no doubt that Picard presented with Irumodic syndrome, enough for his time-jumps to be considered just one of the symptoms.